Area insight
Charities operating throughout England and Wales
Registered charities whose operating area is listed as throughout England and Wales, ranked by latest reported income in the imported high-value sample.
Charities ranked50Limited to the current selected high-value sample.
Combined income£16,413,471,607Latest reported income across this page.
Combined expenditure£16,969,126,763Latest reported expenditure across this page.
Area labelThroughout England And WalesOfficial region operating area.
| Rank | Charity | Income | Expenditure | Period | Status |
|---|---|---|---|---|---|
| 1 | Nuffield Health205533 | £1,484,700,000 | £1,543,500,000 | 31 Dec 2025 | Registered |
| 2 | The Charities Aid Foundation268369 | £1,390,589,000 | £1,231,327,000 | 30 Apr 2025 | Registered |
| 3 | The National Trust for Places of Historic Interest or Natural Beauty205846 | £766,195,000 | £824,377,000 | 28 Feb 2025 | Registered |
| 4 | Cancer Research UK1089464 | £734,753,802 | £714,723,789 | 31 Mar 2025 | Registered |
| 5 | UBS UK Donor-Advised Foundation1153551 | £678,813,000 | £324,660,000 | 31 Dec 2025 | Registered |
| 6 | Wellcome Trust210183 | £589,458,608 | £2,051,212,819 | 30 Sept 2025 | Registered |
| 7 | The Ormiston Trust1164358 | £436,907,000 | £375,599,000 | 31 Aug 2025 | Registered |
| 8 | British Heart Foundation225971 | £410,600,000 | £427,100,000 | 31 Mar 2025 | Registered |
| 9 | The Girls' Day School Trust306983 | £373,418,000 | £345,396,000 | 31 Aug 2025 | Registered |
| 10 | Canterbury Christ Church University1098136 | £353,761,000 | £356,655,000 | 31 Jul 2025 | Registered |
| 11 | Barnardo's216250 | £340,251,582 | £326,609,720 | 31 Mar 2025 | Registered |
| 12 | Change, Grow, Live1079327 | £339,714,761 | £340,389,290 | 31 Mar 2025 | Registered |
| 13 | The Salvation Army214779 | £338,297,000 | £331,868,000 | 31 Mar 2025 | Registered |
| 14 | Quadrature Charitable Foundation1187301 | £336,123,805 | £314,872,107 | 31 Dec 2025 | Registered |
| 15 | Founders Pledge Ltd1162201 | £330,974,528 | £249,984,351 | 31 Dec 2025 | Registered |
| 16 | MSI Reproductive Choices265543 | £330,096,000 | £319,147,000 | 31 Dec 2025 | Registered |
| 17 | The Eric Wright Charitable Trust1002966 | £308,912,000 | £303,038,000 | 31 Dec 2024 | Registered |
| 18 | The British Red Cross Society220949 | £293,500,000 | £304,700,000 | 31 Dec 2025 | Registered |
| 19 | The Shaw Trust Limited287785 | £291,074,000 | £289,069,000 | 31 Aug 2025 | Registered |
| 20 | The Royal National Lifeboat Institution209603 | £286,700,000 | £258,100,000 | 31 Dec 2025 | Registered |
| 21 | Methodist Homes1083995 | £283,275,000 | £285,223,000 | 31 Mar 2025 | Registered |
| 22 | CITB264289 | £280,172,000 | £298,780,000 | 31 Mar 2025 | Registered |
| 23 | AQA Education1073334 | £280,125,196 | £266,419,011 | 31 Mar 2025 | Registered |
| 24 | The Save the Children Fund213890 | £262,508,000 | £275,822,000 | 31 Dec 2025 | Registered |
| 25 | Royal Mencap Society222377 | £247,339,000 | £245,638,000 | 31 Mar 2026 | Registered |
| 26 | The Francis Crick Institute Limited1140062 | £246,171,125 | £254,858,900 | 31 Mar 2025 | Registered |
| 27 | Macmillan Cancer Support261017 | £245,546,254 | £225,920,085 | 31 Dec 2024 | Registered |
| 28 | The Salvation Army Social Work Trust215174 | £239,727,000 | £235,035,000 | 31 Mar 2025 | Registered |
| 29 | The Orders of St John Care Trust1048355 | £233,636,544 | £234,288,650 | 31 Mar 2025 | Registered |
| 30 | Canal & River Trust1146792 | £232,600,000 | £233,400,000 | 31 Mar 2025 | Registered |
| 31 | National Philanthropic Trust UK Limited1181128 | £225,406,809 | £44,403,998 | 30 Jun 2025 | Registered |
| 32 | Royal Society for the Protection of Birds207076 | £194,964,000 | £176,791,000 | 31 Mar 2025 | Registered |
| 33 | Royal Opera House Covent Garden Foundation211775 | £182,080,000 | £174,656,000 | 25 Aug 2025 | Registered |
| 34 | Marie Curie207994 | £181,101,000 | £189,636,000 | 31 Mar 2025 | Registered |
| 35 | UBS Optimus Foundation UK1153537 | £178,158,000 | £181,193,000 | 31 Dec 2025 | Registered |
| 36 | The City and Guilds of London Institute312832 | £174,800,000 | £182,400,000 | 31 Aug 2025 | Registered |
| 37 | Dogs Trust1167663 | £172,342,000 | £162,805,000 | 31 Dec 2025 | Registered |
| 38 | General Medical Council1089278 | £171,548,472 | £160,097,269 | 31 Dec 2025 | Registered |
| 39 | Royal Society for the Prevention of Cruelty to Animals219099 | £171,503,000 | £185,184,000 | 31 Dec 2025 | Registered |
| 40 | Stewardship Services (Uket) Limited234714 | £170,918,545 | £144,476,318 | 31 Dec 2025 | Registered |
| 41 | The Royal British Legion219279 | £168,476,000 | £177,614,000 | 30 Sept 2025 | Registered |
| 42 | The National Association of Citizens Advice Bureaux279057 | £167,831,000 | £166,480,000 | 31 Mar 2025 | Registered |
| 43 | UK Online Giving Foundation1164887 | £166,341,000 | £165,896,000 | 31 Mar 2025 | Registered |
| 44 | The Julia Rausing Trust1213572 | £165,763,576 | £132,897,456 | 31 Dec 2025 | Registered |
| 45 | Garfield Weston Foundation230260 | £165,443,000 | £130,839,000 | 05 Apr 2025 | Registered |
| 46 | The Guide Dogs for the Blind Association209617 | £163,800,000 | £151,700,000 | 31 Dec 2025 | Registered |
| 47 | Action for Children1097940 | £163,445,000 | £163,026,000 | 31 Mar 2025 | Registered |
| 48 | The Royal Society of London for Improving Natural Knowledge (Commonly Known as the Royal Society)207043 | £157,614,000 | £151,520,000 | 31 Mar 2025 | Registered |
| 49 | The Master Charitable Trust1139904 | £155,287,000 | £174,535,000 | 30 Sept 2025 | Registered |
| 50 | JISC1149740 | £150,710,000 | £165,264,000 | 31 Jul 2025 | Registered |
Quality note
This page uses self-reported operating area records from the Charity Commission extract. It does not mean all listed charities are headquartered in this area, and deeper profile pages require enough source-backed context to avoid thin register copies.