Cause insight
Health and life-saving charities
Health and life-saving charities from the current public register extract, with income, spending, filing period, and source caveats.
Charities ranked50Limited to the current selected high-value sample.
Combined income£13,625,426,272Latest reported income across this page.
Combined expenditure£15,196,514,906Latest reported expenditure across this page.
ClassificationThe Advancement Of Health Or Saving Of LivesOfficial Charity Commission classification label.
| Rank | Charity | Income | Expenditure | Period | Status |
|---|---|---|---|---|---|
| 1 | Nuffield Health205533 | £1,484,700,000 | £1,543,500,000 | 31 Dec 2025 | Registered |
| 2 | Save the Children International1076822 | £955,412,235 | £955,712,819 | 31 Dec 2025 | Registered |
| 3 | Cancer Research UK1089464 | £734,753,802 | £714,723,789 | 31 Mar 2025 | Registered |
| 4 | Lloyd's Register Foundation1145988 | £691,735,000 | £662,433,000 | 30 Jun 2025 | Registered |
| 5 | Cardiff University1136855 | £634,070,682 | £692,020,576 | 31 Jul 2025 | Registered |
| 6 | Wellcome Trust210183 | £589,458,608 | £2,051,212,819 | 30 Sept 2025 | Registered |
| 7 | British Heart Foundation225971 | £410,600,000 | £427,100,000 | 31 Mar 2025 | Registered |
| 8 | Oasis Charitable Trust1026487 | £344,497,000 | £313,851,000 | 31 Aug 2025 | Registered |
| 9 | Change, Grow, Live1079327 | £339,714,761 | £340,389,290 | 31 Mar 2025 | Registered |
| 10 | The Salvation Army214779 | £338,297,000 | £331,868,000 | 31 Mar 2025 | Registered |
| 11 | MSI Reproductive Choices265543 | £330,096,000 | £319,147,000 | 31 Dec 2025 | Registered |
| 12 | The British Red Cross Society220949 | £293,500,000 | £304,700,000 | 31 Dec 2025 | Registered |
| 13 | The Royal National Lifeboat Institution209603 | £286,700,000 | £258,100,000 | 31 Dec 2025 | Registered |
| 14 | Royal Commonwealth Society for the Blind207544 | £283,836,000 | £288,392,000 | 31 Dec 2025 | Registered |
| 15 | Methodist Homes1083995 | £283,275,000 | £285,223,000 | 31 Mar 2025 | Registered |
| 16 | The Save the Children Fund213890 | £262,508,000 | £275,822,000 | 31 Dec 2025 | Registered |
| 17 | The Francis Crick Institute Limited1140062 | £246,171,125 | £254,858,900 | 31 Mar 2025 | Registered |
| 18 | Macmillan Cancer Support261017 | £245,546,254 | £225,920,085 | 31 Dec 2024 | Registered |
| 19 | Islamic Relief Worldwide328158 | £238,998,821 | £241,049,736 | 31 Dec 2025 | Registered |
| 20 | St Andrew's Healthcare1104951 | £235,558,118 | £233,717,760 | 31 Mar 2025 | Registered |
| 21 | Community Integrated Care519996 | £197,363,000 | £195,589,000 | 31 Mar 2025 | Registered |
| 22 | Turning Point234887 | £192,496,000 | £191,535,000 | 31 Mar 2025 | Registered |
| 23 | Trustees of the London Clinic Limited211136 | £188,080,000 | £210,783,000 | 31 Dec 2024 | Registered |
| 24 | Marie Curie207994 | £181,101,000 | £189,636,000 | 31 Mar 2025 | Registered |
| 25 | Genome Research Limited1021457 | £180,349,000 | £183,494,000 | 30 Sept 2025 | Registered |
| 26 | UBS Optimus Foundation UK1153537 | £178,158,000 | £181,193,000 | 31 Dec 2025 | Registered |
| 27 | General Medical Council1089278 | £171,548,472 | £160,097,269 | 31 Dec 2025 | Registered |
| 28 | The Royal British Legion219279 | £168,476,000 | £177,614,000 | 30 Sept 2025 | Registered |
| 29 | The National Association of Citizens Advice Bureaux279057 | £167,831,000 | £166,480,000 | 31 Mar 2025 | Registered |
| 30 | The Halo Trust1001813 | £165,647,000 | £163,115,000 | 31 Mar 2025 | Registered |
| 31 | Walsall Housing Group Limited1108779 | £155,448,068 | £131,076,678 | 31 Mar 2025 | Registered |
| 32 | The Master Charitable Trust1139904 | £155,287,000 | £174,535,000 | 30 Sept 2025 | Registered |
| 33 | Cardiff Metropolitan University1140762 | £148,589,000 | £146,766,000 | 31 Jul 2025 | Registered |
| 34 | The United Kingdom Committee for UNICEF1072612 | £146,653,000 | £145,761,000 | 31 Dec 2025 | Registered |
| 35 | Denise Coates Foundation1149110 | £143,968,000 | £18,990,000 | 26 Mar 2025 | Registered |
| 36 | Alzheimer's Society296645 | £143,833,000 | £148,992,000 | 31 Mar 2025 | Registered |
| 37 | Great Ormond Street Hospital Children's Charity1160024 | £140,352,000 | £348,011,000 | 31 Mar 2025 | Registered |
| 38 | International Medical Corps (UK)1093861 | £136,357,320 | £127,814,692 | 30 Jun 2025 | Registered |
| 39 | Age UK1128267 | £131,786,000 | £135,081,000 | 31 Mar 2025 | Registered |
| 40 | Liverpool School of Tropical Medicine222655 | £129,330,000 | £127,136,000 | 31 Jul 2025 | Registered |
| 41 | The Football Foundation1079309 | £128,173,000 | £115,327,000 | 31 Mar 2026 | Registered |
| 42 | St Mungo Community Housing Association1149085 | £124,000,694 | £124,486,370 | 31 Mar 2025 | Registered |
| 43 | HCT Group1091318 | £123,706,829 | £133,744,285 | 30 Sept 2020 | Registered |
| 44 | International Planned Parenthood Federation229476 | £122,734,320 | £103,989,250 | 31 Dec 2025 | Registered |
| 45 | The CH Foundation (UK)1156222 | £119,276,958 | £100,161,531 | 31 Mar 2025 | Registered |
| 46 | Camfed International1029161 | £117,496,794 | £85,061,334 | 31 Dec 2025 | Registered |
| 47 | The Against Malaria Foundation1105319 | £113,932,411 | £137,190,723 | 30 Jun 2025 | Registered |
| 48 | Walk Wheel Cycle Trust326550 | £110,673,000 | £113,620,000 | 31 Mar 2025 | Registered |
| 49 | Nursing and Midwifery Council1091434 | £108,669,000 | £130,433,000 | 31 Mar 2025 | Registered |
| 50 | Sue Ryder1052076 | £104,682,000 | £109,060,000 | 31 Mar 2026 | Registered |
Quality note
This page is a classification-based research aid. It does not claim these are the best charities in the cause area, and it currently ranks only the selected high-income sample imported into D1. Deeper profile pages require enough source-backed context to avoid thin register copies.